Season Two
- #40: The Case of the Corresponding Corpse 9/20/58
- Joan Camden as Ruth Whittaker
- Vaughn Taylor as Harry Folsom
- Jeanne Cooper as Laura Beaumont
- William Ching as Glenn McKay
- Ross Elliott as George Beaumont
- Owen Cunningham as Jonah Whittaker
- Lillian Bronson as Judge
- Herbert C. Lytton as Mr. Corby
- Martha Wentworth as Mrs. Lyle
- Joan Staley as Roberta Quinn
- Gil Frye as Reporter
- Jack Gargan as Court Clerk
- #41: The Case of the Lucky Loser 9/27/58
- Patricia Medina as Harriet Balfour
- Bruce Bennett as Lawrence Balfour
- Heather Angel as Florence Ingle
- Douglas Kennedy as Steven Boles
- Tyler MacDuff as Ted Balfour
- Richard Hale as Addison Balfour
- Woodrow Chambliss as Fred Haley
- John Eldrege as Thurston
- Morris Ankrum as Judge Cadwell
- Guy Rennie as Roger Faris
- Paul Genge as Sergeant
- John Bleifer as Schmidt
- Jack Holland as Ballistics Expert
- Len Hendry as Policeman
- #42: The Case of the Pint-Sized Client 10/4/58
- Eduardo Ciannelli as Gramp Renzi
- Nita Talbot as Iris Anderson
- Elisha Cook as Art Crowley
- Bobby Clark as Nicky Renzi
- James Anderson as Frank Anderson
- Otto Waldis as Mr. Kolichek
- Robert Lieb as Charles Hays
- Eleanor Audley as Lois Gilbert
- Joseph Mell as George Koch
- Raymond Greenleaf as Judge
- Paul Bryar as Sgt. Bender
- Edward Marr as Cagle
- Than Wyenn as Eddie Merlin
- #43: The Case of the Sardonic Sergeant 10/11/58
- John Dehner as Major Lewis
- Robert Armstrong as Walter Haskell
- Lori March as Helen Lessing
- John Archer as Major Frank Lessing
- Larry Jackson as M Sgt. William Smith
- Grant Richards as Capt. Kennedy
- Paul Picerni as Sgt. Joseph Dexter
- Wendell Holmes as Howard Evans
- Barbara Luna as Rikki Stevens
- Kevin Hagen as Sgt. Burke
- Russell Thorson as Lt. Col. Brice
- George E. Stone as Bartender
- Lee Torrance as Sgt. 1st Class McKnight
- Rand Harper as Lt. Walker
- Hal Torey as Mr. Blake
- Helene Heigh as Mrs. Agnes Haskell
- Vance Howard as Court Clerk
- #44: The Case of the Curious Bride 10/18/58
- Christine White as Rhoda Reynolds
- Casey Adams as Carl Reynolds
- John Hoyt as Philip Reynolds
- Michael Emmet as Arthur Kane
- James Seay as Dr. Harris
- Dorothy Neuman as Ellen Crandall
- Tommy Cook as Frank Lane
- Peggy Maley as Edna Freeman
- Lewis Charles as Sidney Otis
- S. John Launer as Judge
- James Nolan as Deputy
- #45: The Case of the Buried Clock 11/1/58
- Don Beddoe as Dr. Blane
- Fredd Wayne as Jack Hardisty
- June Dayton as Sue Hardisty
- Jeanne Bates as Jean Strague
- Paul Fix as District Attorney Hale
- Charles Cooper as Philip Strague
- Robert Foulk as Sheriff Elmore
- Robin Hughes as Rodney Beaton
- Howard Wendell as A. J. Randall
- Harry Tyler as Court Clerk
- Paul Serra as Davis
- Gil Frye as Faulkner
- Jamie Forster as Judge Norwood
- Phil Chambers as Dr. Ritchie
- Don Kennedy as Deputy Sheriff
- #46: The Case of the Married Moonlighter 11/8/58
- Arthur Franz as Danny Harrison
- Jesse White as Luke Hickey
- Anne Sargent as Eileen Harrison
- Stacy Harris as Frank Curran
- Frances Helm as Linda Kennedy
- Douglas Evans as Phil McCabe
- Tom Palmer as George Palmer
- Richard Gaines as Judge Carwell
- Olan Soule as Court Clerk
- Fern Barry as Mrs. Cunningham
- Carol Anderson as The Model
- #47: The Case of the Jilted Jockey 11/15/58
- Billy Pearson as Tic Barton
- Barbara Lawrence as Gloria Barton
- June Vincent as Victoria Bannion
- Don Durant as Johnny Starr
- Joe di Reda as Eddie Davis
- Hugh Sanders as Dion Bannion
- Nolan Leary as Bob Allen
- Kenneth R. MacDonald as Judge
- Roy Engel as Mr. Horty
- Joe Forte as Coroner
- #48: The Case of the Purple Woman 11/22/58
- George Macready as Milo Girard
- Bethel Leslie as Evelyn Girard
- Robert H. Harris as Aaron Hubble
- Rhys Williams as Rufus Varner
- Doris Singleton as Doris Andrews
- Donald Murphy as Wayne Gordon
- Stephen Bekassy as Laslo Kovac
- Edwin Jerome as Judge
- Shirley Houser as Waitress
- #49: The Case of the Fancy Figures 12/13/58
- Frank Silvera as Jonathan Hyett
- Joan Banks as Valerie Brewster
- Anne Barton as Carolyn Ellis
- William Phipps as Martin Ellis
- Ralph Clanton as Charles Brewster
- Ray Kellogg as Richard Hyett
- Harvey Stephens as Victor Squires
- S. John Launer as Judge
- Chuck Webster as Sgt. Brice
- Leslie Kimmell as Mailman
- David McMahon as Walter Vico
- #50: The Case of the Perjured Parrot 12/20/58
- Edgar Buchanan as Andy Templet
- Jody Lawrance as Ellen Monteith
- Dan Barton as Richard Waid
- Fay Baker as Stephanie Sabin
- Robert E. Griffin as Fred Bascomb
- Frank Ferguson as Sheriff Barnes
- Joe Kearns as Mr. Langley
- Jason Johnson as District Attorney R. Sprague
- Maurice Manson as Charles Sabin
- Pamela Branch as Helen Watkins
- Jesslyn Fax as Court Clerk
- Howard Culver as Rufus Bolding
- #51: The Case of the Shattered Dream 1/3/59
- Osa Massen as Sarah Werner
- Marion Marshall as Irene Bedford
- Virginia Vincent as Virginia Trent
- Kurt Kreuger as Hans Breel
- Chris Alcaide as Jerry Morrow
- Ludwig Stossel as Adolph Van Beers
- Ivan Triesault as Fred Schoenbeck
- Theodore Marcuse as William Walker
- Lillian Bronson as Judge
- Robert Carson as Lawrence David
- Gil W. Rankin as Autopsy Surgeon
- Cy Malis as Hilton
- Barry Brooks as Dealer
- Brandy Bryan as Doris
- #52: The Case of the Borrowed Brunette 1/10/59
- Maggie Mahoney as Eva Martell
- Paula Raymond as Helen Reynolds
- Sheila Bromley as Agnes Nulty
- Adrienne Marden as Barbara Slater
- John Stephenson as Grant Reynolds
- Joe De Santis as Melvin Slater
- Morris Ankrum as Judge Bates
- Herman Rudin as Thomas Folsom
- Gisele Verlaine as Secretary
- Howard Van Proyen as Samuel Dixon
- Fred Rapport as Clerk
- #53: The Case of the Glittering Goldfish 1/17/59
- Cecil Kellaway as Darrell Metcalf
- May Wynn as Donna Sherwood
- John Hudson as Tom Wyatt
- Jacqueline Scott as Sally Wilson
- Catherine McLeod as Nora Huxley
- Willard Sage as Dan Myers
- Gage Clarke as Frederick Rollins
- Murvyn Vye as Jack Huxley
- S. John Launer as Judge
- Rusty Lane as Harry Tiller
- Olan Soulé as Clerk
- Chuck Webster as Sgt. Brice
- #54: The Case of the Foot-Loose Doll 1/24/59
- Barton MacLane as Senator Baylor
- Robert Bray as Carl Davis
- Ruta Lee as Millie Crest
- Betty Lou Gerson as Marjory Davis
- Eve McVeagh as Laura Richards
- Sam Buffington as Fred Ernshaw
- Richard Gaines as Judge
- Susan Dorn as Grace
- Helene Stanley as Fern Driscoll
- Jim Kirkwood, Jr. as Johnny Baylor
- John Bryant as Bob Wallace
- Jan Harrison as Patient
- Charles Meredith as Doctor
- Carol Byron as 1st Girl
- Lee Miller as Sgt. Brice
- Jack Harris as Court Clerk
- #55: The Case of the Fraudulent Foto 2/7/59
- Hugh Marlowe as Brander Harris
- Carole Mathews as Leora Mathews
- Wilton Graff as Cleveland Blake
- June Clayworth as Eva Scott
- Mark Roberts as James Castleton
- Bartlett Robinson as Marshall Scott
- Carol Nugent as Helen Preston
- Peter Brocco as Theophile Duclerc
- Kenneth R. MacDonald as Judge
- Herbert Anderson as Eugene Milton
- Francis De Sales as George Fairbanks
- Nancy Millard as Switchboard Operator
- Irving Mitchell as Autopsy Surgeon
- Arline Hunter as Receptionist
- #56: The Case of the Romantic Rogue 2/14/59
- Marion Ross as Helen Harvey
- Albert Linville as Harry West
- Sara Haden as Florence Harvey
- John Bryant as Stacey Chandler
- Peggy Maley as Margo Lawrence
- Jean Willes as Irene Wallace
- Jack Daly as Pete Daniels
- Frederic Worlock as Judge
- Pitt Herbert as Autopsy Surgeon
- Don Dillaway as Robert Riley
- Lee Miller as Sergeant Brice
- Robert Bice as Faulkner
- #57: The Case of the Jaded Joker 2/21/59
- Frankie Laine as Danny Ross
- Bobby Troup as Buzzie
- Walter Burke as Freddie Green
- Tom Drake as Cleve Niles
- Mary LaRoche as Lisa Hiller
- Martha Vickers as Sheila Hayes
- Harry Jackson as Charles Goff
- S. John Launer as Judge
- Jon Lormer as Coroner
- #58: The Case of the Caretaker's Cat 3/7/59
- Benson Fong as James Hing
- John G. Agar as Kenneth Baxter
- Robert Knapp as Stuart Baxter
- Maxine Cooper as Edith Devoe
- Judy Lewis as Winifred Oakley
- Dick Crane as Dr. Douglas Keene
- Raymond Bailey as Mr. Hilliard
- Anthony Eustrel as Gordon Roland
- Barney Biro as Judge
- Bill Erwin as Paint Store Clerk
- Michael Fox as Autopsy Surgeon
- Anthony Jochim as Peter Baxter
- George E. Stone as Court Clerk
- Jacqueline Lee as Nurse Watson
- #59: The Case of the Stuttering Bishop 3/14/59
- Vaughn Taylor as Bishop Mallory
- Ken Lynch as Wallace Lang
- Herb Ellis as Deputy District Attorney
- Rebecca Welles as Carol Delaney
- Joan Vohs as Janice Burroughs
- Jonathan Kidd as Philip Burroughs
- Carl Benton Reid as Charles Burroughs
- Peter Garey as Larry Kenyon
- Morris Ankrum as Judge
- Jon Lormer as Doctor
- Claire Carleton as Blanche Atkins
- Killer Karl Davis as Leo Kaster
- George E. Stone as Court Clerk
- Jim Brandt as Teenage Boy
- Lee Miller as Sgt. Brice
- Hubie Kerns as Skin Diver
- #60: The Case of the Lost Last Act 3/21/59
- Joanne Gilbert as Faith Foster
- Katharine Bard as Helen Dwight
- Jerome Cowan as Royce
- Stacy Harris as Frank Brooks
- Richard Erdman as Jim West
- David Lewis as John Gifford
- Robert McQueeney as Michael Dwight
- Richard Gaines as Judge
- Connie Cezon as Gertie
- George E. Stone as Court Clerk
- #61: The Case of the Bedeviled Doctor 4/4/59
- Dick Foran as Dr. David Craig
- Marianne Stewart as Edith Douglas
- Norma Moore as Dana Lewis
- Phillip Terry as Peter Heywood
- Barry McGuire as Mark Douglas
- Allen Case as Ronny Fowler
- Andrea King as Barbara Heywood
- Frederic Worlock as Judge
- Michael Fox as Dr. Hexie
- George E. Stone as Court Clerk
- John McKee as Faulkner
- Jane Eagar as Martha
- #62: The Case of the Howling Dog 4/11/59
- Ann Rutherford as Evelyn Forbes
- Fintan Meyler as Thelma Brent
- Robert Ellenstein as Arthur Cartright
- Elaine Edwards as Polly Forbes
- Gregory Walcott as Bill Johnson
- John Holland as Clinton Forbes
- Tom Greenway as Rod Andrews
- Grace Raynor as Marilyn Storm
- Ed Prentiss as Dr. Bayliss
- S. John Launer as Judge
- Vito Scotti as D'Amato
- Pitt Herbert as Coroner
- George E. Stone as Court Clerk
- Marcia Drake as Nurse
- Frank Hagney as Watchman
- Lee Miller as Sgt. Brice
- #63: The Case of the Calendar Girl 4/18/59
- Dolores Donlon as Dawn Manning
- John Anderson as George Andrews
- Kasey Rogers as Loretta Harper
- Dean Harens as Frank Fettridge
- George Neise as Wilfred Borden
- Charles Tannen as Jasper Horn
- Evelyn Scott as Beatrice Cornell
- Ralph Moody as Dennison
- Richard Gaines as Judge
- Jon Lormer as Autopsy Surgeon
- George E. Stone as Court Clerk
- Thom Conroy as Head Waiter
- Diana Crawford as Patti Drew
- Doug Marland as Bob
- #64: The Case of the Petulant Partner 4/25/59
- R. G. Armstrong as Harry Bright
- William H. Wright as Chuck Clark
- Francis J. McDonald as Salty Sims
- Geraldine Wall as Nell Gridley
- Nan Leslie as Margaret Clark
- Myron Healey as Howard Roper
- William Swan as Bill Shayne
- Russell Thorson as Mel Topham
- Lynne Allen as Louise Dayton
- Jamie Forster as Judge
- Russ Bender as Sgt. Givens
- Stafford Repp as Philip Morgan
- Sid Cassel as Waiter
- Steve Stevens as Bellboy
- Tony Regan as Kellogg
- #65: The Case of the Dangerous Dowager 5/9/59
- Robert Strauss as Danny Barker
- Patricia Cutts as Sylvia Oxman
- Kathryn Givney as Matilda Benson
- Barry Atwater as Robert Benson
- Michael Dante as Arthur Manning
- Gene Blakely as Frank Oxman
- Leo Gordon as Charles Duncan
- Ellen Corby as Old Lady
- King Calder as Dr. Ralph Caldwell
- Frederic Worlock as Judge
- Joey Faye as Walter Cobb
- George E. Stone as Court Clerk
- Perry Cook as Old Man
- Barry Brooks as Policeman
- Shirley Monticue as Maid
- #66: The Case of the Deadly Toy 5/16/59
- Mala Powers as Claire Allison
- Max Adrian as Ralph Jennings
- Robert Rockwell as Dick Benedict
- Dennis Patrick as Martin Selkirk
- Jennifer Howard as Lorraine Jennings
- Paul Cavanagh as Horace Selkirk
- Kathryn Card as Hannah Barton
- Nancy Kulp as Katherine Collins
- Morris Ankrum as Judge
- Norm Alden as Darrel Reed
- David Brady as David Selkirk
- Pitt Herbert as Autopsy Surgeon
- Nina Stevens as Nurse
- Richard Hervey as Counterman
- George E. Stone as Court Clerk
- Lee Miller as Sgt. Brice
- Bob Howard as Bill Evans
- #67: The Case of the Spanish Cross 5/30/59
- Jacques Aubuchon as Felix Karr
- Josephine Hutchinson as Miriam Baker
- Richard Miles as Jimmy Morrow
- Linda Watkins as Grace Runyan
- Arthur Space as James Morrow, Sr.
- Donald Randolph as Curtis Runyan
- Jonathan Hole as Everett Wormser
- Richard Gaines as Judge
- Harlan Warde as Sgt. Kenton
- Herman Rudin as Roger
- George E. Stone as Court Clerk
- Chuck Zacha as Harry Kline
- #68: The Case of the Dubious Bridegroom 6/13/59
- Betsy Jones Moreland as Lorrie Garvin
- Jean Tabor as Virginia Colfax
- Patrick McVey as Covington
- Harry Ellerbe as Edward Garvin
- K. T. Stevens as Ethel Garvin
- Thomas Browne Henry as George Denby
- Neil Hamilton as Frank Livesey
- Tom Brown as Jarvis
- Robert Nichols as Howard Scanlon
- Rosa Turich as Filomena
- Robert Lynn as Judge
- Keith Richards as Sergeant Holt
- James Nolan as Policeman
- Dick Keene as Court Clerk
- #69: The Case of the Lame Canary 6/27/59
- James Philbrook as Harry Jonson
- Stacy Graham as Ruth Prescott
- Biff Elliot as Jimmy McLain
- Susan Cummings as Margaret Swaine
- William Kendis as Walter Prescott
- Berry Kroeger as Ernest Wray
- S. John Launer as Judge
- Michael Fox as Dr. Hoxie
- Emerson Treacy as Dr. Fowler
- Chet Stratton as Hotel Clerk
- Ray Phillips as Police Officer
- Lee Miller as Sgt. Brice
- George E. Stone as Court Clerk
- Richard Wessel as Transfer Man