Season Five
- #124: The Case of the Jealous Journalist 9/2/61
- Irene Hervey as Grace Davies
- Jan Merlin as Ralph Quentin
- Linden Chiles as Joe Davies
- Denver Pyle as Tilden Stuart
- Bek Nelson as Miriam Coffey
- Theodore Marcuse as Boyd Alison
- Claire Griswold as Kerry Worden
- Parley Baer as Seward Quentin
- Paul Smith as Bartender
- Frieda Inescort as Hope Quentin
- Roxanne Arlen as Bonnie Mae
- Lee Giroux as Newscaster
- James D. Neilson as Operative
- Alex Bookston as Lewis
- Tom Harkness as Judge
- Richard Geary as Searcher
- #125: The Case of the Impatient Partner 9/16/61
- Ben Cooper as Frank Wells
- Leslie Parrish as Vivian Ames
- Wesley Lau as Amory Fallon
- Lucy Prentis as Edith Fallon
- Peter Adams as Ned Thompson
- Mary Young as Mrs. Murdock
- Cheerio Meredith as Mrs. Temple
- Jack Betts as Bert Nickols
- Dan Seymour as Carlos Silva
- Chet Stratton as Charles Grant
- Barney Biro as Judge
- Charles Stroud as Court Clerk
- Paula Courtland as Margo
- #126: The Case of the Missing Melody 9/30/61
- Constance Towers as Jonny Baker
- James Drury as Eddy King
- Bobby Troup as Bongo White
- Jo Morrow as Polly Courtland
- Karl Held as David Gideon
- Andrea King as Enid Markham
- Walter Burke as Jack Grabba
- Grant Richards as George Sherwin
- Lorrie Richards as Midge Courtland
- Crahan Denton as Templeton Courtland
- Barney Kessel as Barney
- Frederic Worlock as Judge
- Owen McGiveney as Boyson
- Lee Miller as Sgt. Brice
- Richard Geary as Detective
- Irving Mitchell as Minister
- Tony Mafia as Waiter
- Jack Williams as First Gambler
- Philip Harron as Second Gambler
- #127: The Case of the Malicious Mariner 10/7/61
- Sean McClory as Wenzel
- Edward Binns as Charles Griffin
- Roy Roberts as Arthur Janeel
- Lee Farr as Griffin
- Karl Held as David Gideon
- Casey Adams as Frank Logan
- Wesley Lau as Lt. Anderson
- Penny Edwards as Julie Abbott
- Robert Armstrong as Capt. Bancroft
- Victor Sen Yung as Sheng
- Tudor Owen as MacLean
- Robert Carson as Capt. Lansing
- George Ives as Lt. Gregg
- Robert Foulk as Vogel
- Kenneth MacDonald as Judge
- Pitt Herbert as Autopsy Surgeon
- Douglas Evans as Capt. Wilson
- George Sawaya as Connor
- Roy Jenson as Officer
- Rollin Moriyama as Nagata
- Gordon Kee as Panjong
- #128: The Case of the Crying Comedian 10/14/61
- Tommy Noonan as Charlie Hatch
- Jackie Coogan as Gunner Grimes
- Gloria Talbott as Ann Gilrain
- Sue Ane Langdon as Rowena
- Med Flory as Sgt. McVey
- Stacy Harris as Ed Brigham
- Liam Sullivan as Tom Gilrain
- John Gallaudet as Judge
- Nestor Paiva as Nico
- John Alvin as Manager
- Louis Mercier as Remy
- Ray Dannis as Reese Lordan
- Art Lewis as M. C.
- Alan Reynolds as Dr. Iverson
- Carl Milletaire as Bolin
- Charles Stroud as Court Clerk
- #129: The Case of the Meddling Medium 10/21/61
- Virginia Field as Sylvia Walker
- Kent Smith as Dr. Arthur Younger
- Mary La Roche as Helen Garden
- Sonya Wilde as Bonnie Craig
- Karl Held as David Gideon
- Paul Smith as Michael Craig
- Ann Carroll as Elaine Paisley
- Lea Marmer as Princess Charlotte
- James Forrest as Philip Paisley
- S. John Launer as Judge
- James Chandler as Sgt. Bradley
- Dr. Andrija Puharich as Dr. Andrija Puharich
- #130: The Case of the Pathetic Patient 10/28/61
- Skip Homeier as Dr. Edley
- Frank Cady as Joe Widlock/Hiram Widlock
- Virginia Gregg as Mrs. Osborn
- Richard Eastham as Prosecutor Parness
- Mort Mills as Sgt. Ben Landro
- Peter Whitney as Roger Gates
- Bek Nelson as Janice Edley
- Edward Kemmer as Leslie Hall
- Charles Irving as Judge
- Wally Brown as Mr. Morgan (Manager)
- Percy Helton as Asa Cooperman
- Bill Erwin as Autopsy Surgeon
- Maura McGiveney as Miss York
- Wayne Heffley as Grif Roland
- Thomas Freebairn-Smith as Banning
- #131: The Case of the Travelling Treasure 11/4/61
- Jeff York as Scot Cahill
- Lisa Gaye as Rita Magovern
- Arch Johnson as Karl Magovern
- H. M. Wynant as Max
- Vaughn Taylor as Prof. Sneider
- Ron Kennedy as Ben Wylie
- Jack Searl as Leon Ulrich
- Addison Richards as Smith
- Baynes Barron as Charlie Bender
- Hardie Albright as Jones
- Frank Gerstle as Allen
- Richard Adams as Jaygee
- Jim Drum as Ambulence Driver
- Nacho Galindo as Mexican Bartender
- Robert Whiting as Assistant
- Gil Frye as Police Officer
- Lee Miller as Sgt. Brice
- Tony Miller as Second Seaman
- Richard Geary as First Seaman
- Tom Harkness as Judge
- Lionel Dante as Watchman
- #132: The Case of the Posthumous Painter 11/11/61
- Stuart Erwin as Austin Durrant
- George Macready as Dr. Vincent Kenyon
- Carol Rossen as Linda Burnside
- Lori March as Edna Culross
- Karl Held as David Gideon
- Wesley Lau as Lt. Anderson
- Jason Evers as Clint Miller
- Britt Lomond as Jack Culross
- James Griffith as Walter Hutchings
- Nelson Leigh as Judge
- John McNamara as Robert Shelby
- Vera Marshe as Woman
- Don Lynch as Deputy
- Paul Barselow as Resident
- Chuck Hamilton as Postal Inspector
- #133: The Case of the Injured Innocent 11/18/61
- John Conte as Kirby Evans
- Frank Maxwell as Dr. Mooney
- Audrey Dalton as Kate Eastman
- Alejandro Rey as Vincent Danielli
- Wesley Lau as Lt. Anderson
- Jess Barker as Walter Eastman
- Linda Lawson as Erin Mooney
- Phil Arthur as Ralph Townley
- Raymond Bailey as Dr. Bell
- Noel Drayton as Ellis
- S. John Launer as Judge
- Pitt Herbert as Autopsy Surgeon
- Cindy Ames as Secretary
- Lee Miller as Sgt. Brice
- #134: The Case of the Left-Handed Liar 11/25/61
- Ed Nelson as Ward Nichols
- Leslie Parrish as Veronica Temple
- Les Tremayne as Bernard Daniels
- Maggie Pierce as Casey Daniels
- Karl Held as David Gideon
- Wesley Lau as Lt. Anderson
- Dabbs Greer as Buzz Farrell
- Alan Baxter as Eugene Houseman
- Joan Banks as Rhonda Houseman
- Richard Derr as Dr. Harrison Berry
- Amzie Strickland as Miss Clara Prentice
- Kenneth MacDonald as Judge
- John Harmon as Lab Technician
- Claude Stroud as Masters
- Barbara Pepper as Fat Woman
- Wallace Rooney as Handwriting Expert
- Henry Hunter as Mr. Baxter
- John Reach as Policeman
- Cynthia Patrick as Woman Fencer
- Lee Miller as Sgt. Brice
- #135: The Case of the Brazen Bequest 12/2/61
- Phyllis Avery as Mary Cromwell
- Alan Hewitt as Dr. Marcus Tate
- Karl Weber as Charles Cromwell
- Mort Mills as Sgt. Landro
- John Wilder as Dick Wilson
- Barbara Stuart as Maizie Freitag
- Strother Martin as Pete Gibson
- Joseph Julian as Deputy D.A. Horner
- William Allyn as Robert Haskell
- Will Wright as James Vardon
- James Millhollin as Prof. Grove
- Charles Irving as Judge
- Elvia Allman as Julia Slovak
- Nelson Olmsted as Dr. Hunterlin
- Dick Whittinghill as Jerry
- Ernest Sarracino as Rafael Sandoval
- Sally Mills as Nurse Talbot
- Charles Tannen as Cabby
- Frank Behrens as Autopsy Surgeon
- Morris Erby as Jonas
- Herbert Lytton as Motel Clerk
- Richard Geary as Deputy Sheriff
- Sandy Shaffer as College Girl
- #136: The Case of the Renegade Refugee 12/9/61
- Frank Overton as Father Paul
- Dick Foran as Harlan Merrill
- Paul Lambert as Lawrence Vander
- John Sutton as Clifton Barlow
- Karl Held as David Gideon
- Wesley Lau as Lt. Anderson
- Ronald Long as Arthur Hennings
- Jennifer Howard as Winifred Dunbrack
- Donna Atwood as Phylis Merrill
- Denver Pyle as Emery Fillmore
- John Gallaudet as Judge
- William Boyett as Buck Osborn
- John Lormer as Autopsy Surgeon
- Robert Nash as Colonel
- Victor Izay as Mr. Jones
- Jess Kirkpatrick as Lou Kouffman
- Lee Miller as Sgt. Brice
- Jo Summers as Miss Gibsone
- #137: The Case of the Unwelcome Bride 12/16/61
- Torin Thatcher as Walter Frazer
- Gerald Mohr as Medeci
- Diana Millay as Sue Ellen
- De Forest Kelley as Peter Thorpe
- Alan Hale as Lon Snyder
- Wesley Lau as Lt. Anderson
- Melora Conway as Amanda Thorpe
- Bryan Grant as Gregson Frazer
- Willis Bouchey as Judge
- Ben Young as Cary Duncan
- George E. Stone as Court Clerk
- Emile Meyer as Patrolman
- #138: The Case of the Roving River 12/30/61
- Sarah Marshall as Judy Bryant
- Bruce Bennett as Matt Lambert
- Paul Fix as Prosecutor
- Philip Ober as Harvey Farrell
- Karl Held as David Gideon
- June Vincent as Chloris Bryant
- J. Pat O'Malley as Seth Tyson
- Harry Carey, Jr. as Frank Deane
- Kelly Thordsen as Sheriff Ward Vincent
- Robert Lowery as Amos Bryant
- Dirk London as Neil Gilbert
- Sherwood Price as Ralph Ordway
- Lewis Martin as Judge Libott
- Ed Prentiss as Judge Holmes
- #139: The Case of the Shapely Shadow 1/6/62
- Robert Rockwell as Cole B. Troy
- Dorothy Green as Carlotta Theilman
- Elaine Devry as Janice Wainwright
- Barbara Lawrence as Mrs. Theilman
- Karl Held as David Gideon
- George Neise as Morley Theilman
- James Callahan as Fred Carlyle
- Willis Bouchey as Judge
- Ray Hemphill as Henry Battle
- John Dennis as Lt. Sophia
- John Zaremba as Autopsy Surgeon
- Hal Smith as Moulage Man
- William McLean as Newsdealer
- Austin Green as Meteorologist
- Ollie O'Toole as Dudley Roberts
- Olan Soulé as Water Company Official
- Phil Arnold as Smitty
- #140: The Case of the Captain's Coins 1/13/62
- Jeremy Slate as Philip Andrews
- Arthur Franz as Evans
- Joan Patrick as Evelyn Farraday
- Jay Novello as Nickolas Trevelian
- Herbert Rudley as Ben Farraday
- Wesley Lau as Lt. Anderson
- Parley Baer as Edward Farraday
- Don Beddoe as Carter Farraday
- Henry Beckman as Garth
- Allison Hayes as Jane Weeks
- Lauren Gilbert as Henry Cosgrove
- Morris Ankrum as Judge
- Eddie Quillan as Photographer
- Tom Palmer as Charles Noymann
- Will J. White as Sailor
- Tafa Lee as Mrs. Ionescu
- #141: The Case of the Tarnished Trademark 1/20/62
- Karl Swenson as Axel Norstaad
- Osa Massen as Lisa Pedersen
- Marie Windsor as Edie Morrow
- Malcolm Atterbury as Maigret
- Phillip Terry as Latham Reed
- Wesley Lau as Lt. Anderson
- Dennis Patrick as Martin Somers
- Morgan Woodward as Carl Pedersen
- Edward Norris as Sam Hadley
- Francis De Sales as Floyd Chapman
- S. John Launer as Judge
- Tommy Farrell as Salesman
- William Tracy as Motel Manager
- Thom Carney as Policeman
- Don Dillaway as Ramsey
- Robert Ball as Clerk
- Stafford Repp as Bartender
- Lisa Davis as Secretary
- James Hansen as Attendant
- Frank Hagney as 1st Workman
- Harry Strang as 2nd Workman
- Ted White as Foreman
- #142: The Case of the Glamorous Ghost 2/3/62
- Mary Murphy as Eleanor Corbin
- Jeanne Cooper as Ethel Belan
- Ziva Rodann as Suzanne Granger
- Merry Anders as Sadie Hepner
- Douglas Dick as Walter Richey
- Wesley Lau as Lt. Anderson
- Coleen Gray as Olga Jordan
- Vinton Hayworth as Homer Corbin
- Kenneth MacDonald as Judge
- Jon Lormer as Dr. Oberon
- Jan Stine as Boy
- Judee Morton as Girl
- Don McGovern as Policeman
- George E. Stone as Court Clerk
- #143: The Case of the Poison Pen-Pal 2/10/62
- Everett Sloane as District Attorney
- Patricia Breslin as Karen Ross
- Douglas Henderson as Peter Gregson
- Bert Freed as Carl Holman
- Wright King as Lee Gregson
- Joan Tompkins as Florence Holman
- Kathryn Givney as Wilma Gregson
- Naomi Stevens as Agnes
- Charles Cooper as Ben Willoughby
- Harry Jackson as Matt Clark
- Paul Genge as Inspector Wade
- John Litel as Judge
- Chrystine Jordan as Sandra Gregson
- Diane Mountford as Jill Thatcher
- Richard St. John as Autopsy Surgeon
- Walter Kelly as Surgeon
- Marshall Reed as First Officer
- Diana Darrin as Mrs. Thatcher
- John McKee as Woodfern
- Sherry Hall as Court Clerk
- Kathy Huber as Nurse
- #144: The Case of the Mystified Miner 2/24/62
- Kathie Brown as Susan Fisher
- Josephine Hutchinson as Amelia Corning
- Carlos Rivas as Alfredo Gomez
- Bartlett Robinson as Endicott Campbell
- Sheila Bromley as Elizabeth Dow
- Wesley Lau as Lt. Anderson
- John Gallaudet as Judge
- Stanja Lowe as Sophia Elliot
- Louise Lorimer as Cindy Hastings
- Patrick Thompson as Carlton Campbell
- Michael Harvey as Ken Lowry
- Helen Brown as Carlotta Jackson
- Maidie Norman as Maid
- Robert J. Stevenson as Myrton Abert
- Lenny Geer as Station Attendant
- Pitt Herbert as Autopsy Surgeon
- Howard Redman as Boy No. 1
- Martin Dean as Boy No. 2
- Christian Pasques as Boy No. 3
- #145: The Case of the Crippled Cougar 3/3/62
- Bill Williams as Mike Preston
- John Howard as Hugh Jamison
- Rita Lynn as Lydia Reynolds
- Mort Mills as Sgt. Ben Landro
- Noah Keen as Harlow Phipps
- John Bryant as Arnold Keith
- Simon Scott as Elliot Dunbar
- Abbagail Shelton as Paula Hamilton
- Tom Fadden as Watchman
- Willis Bouchey as Judge
- Shary Marshall as Girl (Airline's Counter)
- Florence Wyatt as Grace Keith
- Joe Benson as Deputy
- #146: The Case of the Absent Artist 3/17/62
- Zasu Pitts as Daphne Whilom
- Mark Roberts as Gabe Phillips/Otto Gervaert
- Richard Erdman as Charles (Monty) Montrose
- Victor Buono as Alexander Glovatski
- Jay Barney as Harry Clark
- Wesley Lau as Lt. Anderson
- Arline Sax as Fiona Cregan
- Wynne Pearce as Pete Manders
- Pamela Curran as Leslie Lawrence
- Carl Don as Myer
- Lane Bradford as Arnold Buck
- Bill Zuckert as Judge
- Barney Phillips as Newburgh
- Mabel Rea as Girl
- Patrick Waltz as Court Clerk
- Wes Bishop as Agnew
- Marshall Kent as Man
- Ann Staunton as Woman
- #147: The Case of the Melancholy Marksman 3/24/62
- Paul Richards as Ted Chase
- Jeff Donnell as Sylvia Dykes
- Mari Blanchard as Irene Chase
- William Schallert as Len Dykes
- Ann Rutherford as Ellen Chase
- Wesley Lau as Lt. Anderson
- Peter Baldwin as Tony Benson
- Jesse White as Cecil
- Edward Ashley as Charles Vale
- Cindy Robbins as Mabel Richmond
- S. John Launer as Judge
- John Harmon as Expert
- John Straub as Doctor
- Jon Lormer as Medical Examiner
- Betsy Hale as Betty Chase
- Shari Lee Bernath as Anne Chase
- #148: The Case of the Angry Astronaut 4/7/62
- James Coburn as General Addison Brand
- Robert Bray as Mitch Heller
- Jeanne Bal as Linda Carey
- Patricia Donahue as Bonnie Winslow
- Steve Brodie as Eddie Lewis
- Wesley Lau as Lt. Anderson
- Paula Raymond as Terry Faye
- John Marley as Matthew Owen
- Robert Casper as Bruce Young
- Richard Grant as Gordon Kendall
- Ned Roberts as Sewell
- Tom Harkness as Judge
- Richard Geary as Attendant
- #149: The Case of the Borrowed Baby 4/14/62
- Hugh Marlowe as Jarvis Baker
- Maria Palmer as Florence Wood
- Corey Allen as Lester Menke
- Nellie Burt as Mrs. Holly Cosgrove
- Kaye Elhardt as Ginny Talbot
- Gregory Morton as Dr. Paul Hogathy
- Sara Taft as Mrs. Leander Kerrick
- Joan Petrone as Lenora Graves
- El Brendel as Court Manager
- Charles Thompson as Antique Car Man
- Kenneth MacDonald as Judge
- Ed Stoddard as Gun Clerk
- Lee Miller as Sgt. Brice
- Charles Stroud as Court Clerk
- #150: The Case of the Counterfeit Crank 4/28/62
- Otto Kruger as August Dalgran
- Jeanette Nolan as Martha Blair
- Don Dubbins as Kenneth
- Connie Hines as Sandra
- John Larkin as Jay Fenton
- Burt Reynolds as Chuck Blair
- Michael King as Don Morley
- William Woodson as Dr. Jackman
- Paul Langton as Bertram Telford
- Charles Irving as Judge #1
- S. John Launer as Judge #2
- William Keene as Bank Teller
- John Hubbard as Joseph Tayback
- Russ Bender as Deputy Bowman
- Barney Biro as Judge #3
- Paul McGuire as Deputy Turner
- David Saber as Joe Fanning
- #151: The Case of the Ancient Romeo 5/5/62
- Jeff Morrow as Franz Lachman
- Rex Reason as Steve Brock
- Harry von Zell as Phil Scharf
- Patricia Huston as Claire Adams
- Antoinette Bower as Ellen Carson
- Wesley Lau as Lt. Anderson
- K. T. Stevens as Margit Bruner
- Kendrick Huxham as Kelvin MacRae
- Robert Cornthwaite as Carl Bruner
- Willis Bouchey as Judge
- Donald Curtis as Amos Martin
- Stafford Repp as Shipping Agent
- Rosemary Day as Helen Finney
- Charles Stroud as Court Clerk
- #152: The Case of the Promoter's Pillbox 5/19/62
- Geraldine Brooks as Miriam Waters
- Dianne Foster as Nelly Lawton
- George Matthews as Mike Flint
- Ben Cooper as Davis Crane
- Linden Chiles as Herbert Simms
- Wesley Lau as Lt. Anderson
- John Lasell as Charlie Corby
- Edmon Ryan as Jerome Stokes
- John Gallaudet as Judge
- Geraldine Wall as Mrs. Simms
- James O'Hara as Kelsey
- Danielle Aubrey as Alice
- Dan Seymour as Markett
- Michael Fox as Autopsy Surgeon
- Ivan Dixon as Parness
- Kitty Kelly as Ethel Mowry
- Chuck Webster as Gustavson
- George Conrad as Chico
- #153: The Case of the Lonely Eloper 5/26/62
- Jack Ging as Danny Pierce
- John Dall as Julian Kirk
- Jana Taylor as Merle Telford
- Joan Staley as Gina Gilbert
- Jorja Curtright as Olivia Langley
- Wesley Lau as Lt. Anderson
- Paul Tripp as Howard Langley
- Billy Halop as Corbett
- Kenneth MacDonald as Judge
- Carol Andreson as Margo Stevens
- John Zaremba as Doctor Wales
- Ralph Reed as Messenger
- Pepper Curtis as Guest
- Maurice Wells as Doctor
- Holly Harris as Doctor's Wife